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Yes, this is another effort to provide more education about Acemannan. The knowledge-base is so large on this subject that I am hoping to shoulder the research burden that busy people are unable to access. Therefore, these videos. Plus, the efficacy of this molecule is so significant that I feel it is important to do all I can to release Acemannan from its best-kept-secret confines. So, in an effort by scientists in the early 80’s to determine what exactly in the aloe plant is the active ingredient, here’s some more input.
In a previous installment, we determined from a study called Stabilized Aloe Vera: Effect on Human Skin Cells that the Fresh Inner Leaf Gel caused a significant increase in fibroblasts in the skin and the more the dosage of Fresh Inner Leaf Gel from the Aloe plant the more the increase in fibroblasts. Fibroblasts are found in connective tissue that play a crucial role in wound healing and tissue repair.
We understand that at this moment in history (1983) Acemannan had not yet been identified. They would soon identify the many other components of the aloe plant including the fact that calcium and magnesium were at the highest levels above other minerals. Also identified were assorted amino acids, proteins, lectins, pectins, carbohydrates, waxes, fatty acids, and sterols. Yes, Fresh Inner Leaf Gel, got some remarkable results, but what exactly was in this gel that achieved those results? That was the question.
Along the way scientists made the assumption that a protein might be responsible for the activity brought to bear by the inner leaf gel’s activity. They fractionated the inner leaf gel, and they separated out different proteins, and each protein was tested in a culture wound-healing model developed by Alice Johnson PhD. I unsuccessfully tried to find more about this model, but it is referenced by Bill McAnalley in his book The Science Behind Aloe and is one of my main resources.
This Alice Johnson model uses fresh intact human skin that grew at a measurable rate. They first added the Fresh Inner Leaf Gel. Upon adding the gel, the skin grew much faster than the skin that they did nothing with. Well of course this was confirmation of earlier testing. But when they tested the various protein fractions, they had hoped that one of the proteins would accelerate the growth of the skin in the culture models; and the search would be over. But none of them did.
Scientists use the word “fractions” quite a bit but understand it simply as each of the components found inside the aloe plant are a fraction (a small portion or segment) of the plant as a whole. And speaking about small, these fragments we are talking about are extracted from 0.5% of what is understood as the solid components of the plant and the remaining 99.5% of the plant is water.
Soon, one of the polysaccharide fractions was isolated, namely Acemannan. In skin cultures like what is described above they applied this stabilized component, this newly discovered fraction, Acemannan, and it demonstrated the same accelerating effect on skin growth in the same way as did the Fresh Inner Leaf Gel.
To confirm this result, they applied the gel components of the aloe plant after the Acemannan had been removed. In other words, Acemannan was NOT present. This test indicated no cell growth. This experiment was repeated several times with the same results. They concluded that the active component was the Acemannan, the polysaccharide fraction.
What is often missed in all this science is the question of how the scientists at Carrington Laboratories, who engaged these Acemannan explorations, how did they really feel about these discoveries. I asked Sam Caster, founder of MannaRelief and Alovea, in a recent interview, who employs Acemannan on both marketing and mission efforts, what he picked up from those scientists in the early days. He was the initial entrepreneur invited in to hear the Acemannan story from these scientists. He said he sat for hours listening to their input about Acemannan. Sam believed what he was being told, did his due diligence with the same studies I present here (and then some), and went on to impact the nutritional market by distributing over $3B of Acemannan globally, as well as disbursing lifesaving Acemannan to medically fragile children affecting 90 countries of the world. What did the scientists at Carrington Laboratories think?
And they just thought this is like the last frontier of science. They were very excited about what they’d seen. They’d done $100 million worth of research at that point, validating the mechanism of action of Acemannan. It was named Acemannan as an abbreviation of its chemical structure. It’s a highly dispersed acetylated beta 1-4 mannan. So Acetylated Beta mannan became Acemannan. That was given to them by the American Chemical Society because they had discovered a new molecule in nature that had never been identified before. So, they knew they had something unique.
My goal is to communicate the evidence that Acemannan is indeed unique and a leading-edge supplement (like none other) from which all people would benefit.
We market Acemannan and use it in mission outreach based on a Social Business 3.0 platform. We match the nutrition you and I purchase and send Acemannan to the most vulnerable around the world. Come on in we’re doing some good.
Meanwhile,
I hope you will always be careful to maintain good works to meet urgent needs and become heroes to your generation.
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